DARZALEX FASPRO® dosing schedules for adult patients with newly diagnosed multiple myeloma*
For adults patients who are newly diagnosed and are transplant ineligible, DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) in combination with bortezomib + melphalan + prednisone (6-week cycle) has the same dosing schedule as DARZALEX® (daratumumab) in combination with bortezomib + melphalan + prednisone.† DARZALEX FASPRO® is a ready-to-use, single-use vial, which includes a fixed dose and no weight-based calculations.1,2
First dose of the every-3-week dosing schedule is given at Week 7.
First dose of the every-4-week dosing schedule is given at Week 55.
*See the Dosage and Administration section of the full Prescribing Information for more detail. When DARZALEX FASPRO® is administered as part of a combination therapy, see the Prescribing Information for dosage recommendations for the other drugs.
†The option of splitting the first dose for DARZALEX® is not applicable to DARZALEX FASPRO®.
ARRs=administration-related reactions; DVMP=DARZALEX FASPRO® (D) + bortezomib (V) + melphalan (M) + prednisone (P).